URSODIOL (Generic for RELTONE)

Metoprolol Tartrate 50mg, Oral tablet

Marijuana

· Severity: Major

· Notes for Consumers: Marijuana can decrease the ability of this medicine to control your blood pressure and heart rate. You may need to monitor your blood pressure and heart rate more often to make sure they are well-controlled. If you check your own blood pressure at home and notice an increase in your blood pressure or heart rate, contact your health care provider.

· Notes for Professionals: Avoid administering marijuana and beta-blockers together as concurrent use may result in decreased beta-blocker efficacy. Marijuana is known to produce significant increases in heart rate and cardiac output lasting for 2-3 hours. Further, rare case reports of myocardial infarction and cardiac arrhythmias have been associated with marijuana use. These marijuana-induced cardiovascular effects may be detrimental to patients requiring treatment with beta-blockers; thus, coadministration of beta-blockers and marijuana should be avoided.

Metoprolol Tartrate 50mg, Oral tablet

Alcohol

· Severity: Major

· Notes for Consumers: Avoid alcoholic drinks when taking Metoprolol extended-release capsules. Alcohol may change how the drug is released in your body. This may cause more side effects or cause the drug to become less effective. Tell your prescriber if you feel your medicine is not working as expected.

· Notes for Professionals: Avoid alcoholic beverages (ethanol) when taking metoprolol extended-release capsules. Alcohol may cause a rapid release of metoprolol from the capsule, possibly resulting in increased side effects and reduced efficacy.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>