RILUZOLE (Generic for RILUTEK)

Riluzole 50mg, Oral tablet

Tobacco

· Severity: Moderate

· Notes for Consumers: Tobacco smoking might speed the removal of Riluzole from the body, but it is not clear if tobacco smoking causes decreased effectiveness of Riluzole. Your prescriber will closely monitor your response to Riluzole treatment. If you plan to stop smoking, let your prescriber know, as the sudden cessation of smoking may result in increased levels of Riluzole, which might lead to side effects like nausea, diarrhea, dizziness, drowsiness, loss of appetite or weakness. Your prescriber will want to monitor your response to Riluzole treatment whenever a change in smoking status occurs.

· Notes for Professionals: Tobacco smokers might eliminate riluzole more quickly than nonsmokers; the significance of this interaction has not been assessed in terms of a need for riluzole dosage adjustment. The sudden cessation of tobacco smoking may result in a reduced clearance of riluzole, despite the initiation of a nicotine replacement product. Patients taking riluzole should be monitored carefully when changes in smoking status occur.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>