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OXYBUTYNIN (ox i BYOO ti nin) treats symptoms of an overactive bladder, such as loss of bladder control or frequent need to urinate. It works by relaxing muscles in the bladder. It belongs to a group of medications called antispasmodics.
Oxybutynin 3.9mg/24h, Transdermal patch - Biweekly
Grapefruit juice
· Severity: Moderate
· Notes for Consumers: Grapefruit juice and grapefruit-containing foods may increase the side effects of oxybutynin. Do not significantly increase grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. Discuss any new or worsening side effects, such as confusion, constipation, dizziness, difficulty with urination, drowsiness, dry mouth and eyes, changes in vision, palpitations, or fast heartbeat with your health care provider. Do not drive or operate machinery until you know how these drugs affect you.
· Notes for Professionals: Oxybutynin is metabolized by CYP3A4. Inhibitors of the CYP3A4 enzyme system, such as grapefruit juice, may alter oxybutynin mean pharmacokinetic parameters. The clinical significance of such interactions is not known; however, the manufacturer recommends that caution be used when oxybutynin is co-administered with CYP3A4 inhibitors.
Oxybutynin 3.9mg/24h, Transdermal patch - Biweekly
Alcohol
· Severity: Moderate
· Notes for Consumers: Do not drink Alcoholic beverages while taking Oxybutynin. You may feel drowsy or more tired if you drink alcohol-containing drinks while taking this drug. Do not drive or operate machinery while drinking alcoholic beverages and until you know how oxybutynin affects you. You may also notice an increase in the frequency of urination while taking Oxybutynin and drinking alcoholic beverages.
· Notes for Professionals: Ethanol is a CNS-depressant and may cause additive sedative effects when used concomitantly with oxybutynin.
Oxybutynin 3.9mg/24h, Transdermal patch - Biweekly
Caffeine-containing Foods/Beverages
· Severity: Mild
· Notes for Consumers: The intake of beverages containing caffeine may decrease the actions of oxybutynin because caffeine may increase urination. You may wish to limit your caffeine intake (including intake of coffee, colas, teas, or herbal supplements) while taking oxybutynin.
· Notes for Professionals: Consuming greater than 400 mg/day caffeine has been associated with the development of urinary incontinence. Caffeine may aggravate bladder symptoms and counteract the effectiveness of drugs used to treat overactive bladder such as oxybutynin.
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Number of Uses:
oxytrol
3.9MG/24HR | PATCH TDSW | 8 units
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