OSMOLEX ER

Amantadine Hydrochloride 129mg, Oral tablet, osmotic laser drilled

Alcohol

· Severity: Major

· Notes for Consumers: Avoid alcohol-containing drinks while taking Amantadine. If you have drink alcoholic drinks while taking Amantadine you may experience dizziness, confusion, or lightheadedness and fainting, especially when standing. If you take an extended-release product of amantadine, you might especially experience serious side effects.

· Notes for Professionals: Patients should avoid ethanol while taking amantadine. Concomitant use with alcohol is not recommended, as it may increase the potential for CNS effects such as dizziness, confusion, lightheadedness, and orthostatic hypotension. In addition, if the patient is using amantadine extended-release (ER), alcohol use may result in amantadine dose-dumping and toxicity.

Amantadine Hydrochloride 129mg, Oral tablet, osmotic laser drilled

Caffeine-containing Foods/Beverages

· Severity: Major

· Notes for Consumers: Limit Caffeine use while taking Amantadine. This includes limiting caffeine intake in foods (examples coffees, colas, teas, and chocolate), in medicines, and in herbal supplements.

· Notes for Professionals: Amantadine used concomitantly with psychostimulants, such as caffeine, can result in increased stimulant effects, such as nervousness, irritability, or insomnia, and can lead to seizures or cardiac arrhythmias. Close monitoring of the patient is recommended.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>