Mexiletine Hcl Food, Alcohol, Supplements and Drug Interactions

MEXILETINE HCL

QTY 60 • 150 MG • Capsule • Near 77381

MEXILETINE (mex IL e teen) treats a fast or irregular heartbeat (arrhythmia). It works by slowing down overactive electric signals in the heart, which stabilizes your heart rhythm. It belongs to a group of medications called antiarrhythmics.

MEXILETINE HCL Lifestyle Interactions

Mexiletine Hydrochloride 150mg, Oral capsule

Tobacco

· Severity: Moderate

· Notes for Consumers: In theory, Tobacco smoking may reduce the effectiveness of Mexilitene, because tobacco smoke contains substances that speed the removal of Mexiletine from the body. Also, Tobacco smoking may increase the blood pressure or contribute to the risk of heart disease and related problems. Alternatively, if you take Mexilitene and suddenly stop Tobacco smoking, you may experience increased or worsening side effects of Mexiletine such as nausea, vomiting, heartburn, stomach upset, dizziness, tremor, or coordination difficulties. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking. Contact your prescriber immediately if you experience chest pain, palpitations, dizziness, fainting or falling spells, shortness of breath, or change in your usual heart beat (fast, slow, or irregular heart beat) while taking Mexiletine.

· Notes for Professionals: Mexiletine may be affected by pharmacokinetic interactions due to tobacco smoking. Tobacco smoke contains polycyclic aromatic hydrocarbons that induce hepatic CYP450 microsomal enzymes. Tobacco smoking has been noted to significantly enhance the rate of elimination of mexiletine, possibly leading to subtherapeutic clinical effects. Conversely, because the effect on hepatic microsomal enzymes is not related to the nicotine component of tobacco, sudden smoking cessation may result in a reduced clearance of mexiletine, despite the initiation of nicotine replacement. Monitor patients carefully for the desired clinical effects when changes in tobacco smoking status occur.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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Prescription prices may vary from pharmacy to pharmacy and are subject to change. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy.

DISCOUNT ONLY - NOT INSURANCE. Discounts are available exclusively through participating pharmacies. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. This program does not make payments directly to pharmacies. Members are required to pay for all prescription purchases. Cannot be used in conjunction with insurance. You may contact customer care anytime with questions or concerns, to cancel your registration, or to obtain further information. This program is administered by Medical Security Card Company, LLC, Tucson, AZ.

*Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2022. Discount percentages represent savings provided off of pharmacies’ retail prices for consumers who do not have a discount program and pay cash.

The day supply is based upon the average dispensing patterns for the specific drug and strength. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice.

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