Brimonidine Tartrate-Timolol Food, Alcohol, Supplements and Drug Interactions

BRIMONIDINE TARTRATE-TIMOLOL (Generic for COMBIGAN)

QTY 5 • 0.2%-0.5% • Drops • Near 77381

BRIMONIDINE; TIMOLOL (bri MOE ni deen; TYE moe lole) is used in the eye to treat open-angle glaucoma and high pressure in the eyes.

BRIMONIDINE TARTRATE-TIMOLOL (Generic for COMBIGAN) Lifestyle Interactions

Brimonidine Tartrate 0.2%, Timolol Maleate 0.5%, Ophthalmic drops, solution

Alcohol

· Severity: Moderate

· Notes for Consumers: Avoid or minimize your intake of Ethanol (alcohol-containing drinks) while taking Brimonidine Eye Solution. You may feel drowsy or more tired; do not drive or operate machinery while taking these products together.

· Notes for Professionals: Based on the sedative effects of brimonidine in individual patients, brimonidine administration has potential to enhance the CNS depressants effects of ethanol.

Brimonidine Tartrate 0.2%, Timolol Maleate 0.5%, Ophthalmic drops, solution

Marijuana

· Severity: Major

· Notes for Consumers: Marijuana can decrease the ability of this medicine to control your blood pressure and heart rate. You may need to monitor your blood pressure and heart rate more often to make sure they are well-controlled. If you check your own blood pressure at home and notice an increase in your blood pressure or heart rate, contact your health care provider.

· Notes for Professionals: Avoid administering marijuana and beta-blockers together as concurrent use may result in decreased beta-blocker efficacy. Marijuana is known to produce significant increases in heart rate and cardiac output lasting for 2-3 hours. Further, rare case reports of myocardial infarction and cardiac arrhythmias have been associated with marijuana use. These marijuana-induced cardiovascular effects may be detrimental to patients requiring treatment with beta-blockers; thus, coadministration of beta-blockers and marijuana should be avoided.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>

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Prescription prices may vary from pharmacy to pharmacy and are subject to change. The pricing estimates given are based on the most recent information available and may change based on when you actually fill your prescription at the pharmacy.

DISCOUNT ONLY - NOT INSURANCE. Discounts are available exclusively through participating pharmacies. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. This program does not make payments directly to pharmacies. Members are required to pay for all prescription purchases. Cannot be used in conjunction with insurance. You may contact customer care anytime with questions or concerns, to cancel your registration, or to obtain further information. This program is administered by Medical Security Card Company, LLC, Tucson, AZ.

*Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2022. Discount percentages represent savings provided off of pharmacies’ retail prices for consumers who do not have a discount program and pay cash.

The day supply is based upon the average dispensing patterns for the specific drug and strength. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice.

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