APOMORPHINE HCL (Generic for APOKYN)

Apomorphine Hydrochloride 10mg/1mL, Solution for injection

Alcohol

· Severity: Major

· Notes for Consumers: You should avoid Alcoholic drinks while taking Apomorphine. Drinking alcohol greatly increases your risk of dizziness, fainting and falls from a serious drop in blood pressure, which could lead to injury.

· Notes for Professionals: Advise patients to avoid alcoholic beverages during apomorphine therapy. Concurrent use of ethanol and apomorphine has resulted in significantly worse orthostatic hypotension compared to apomorphine alone. Coadministration of low dose ethanol (0.3 grams/kg) with subcutaneous apomorphine in healthy subjects did not have a significant effect on the pharmacokinetics of apomorphine; however, high dose ethanol (0.6 grams/kg), equivalent to about 3 standardized alcohol-containing beverages, increased the maximum concentration of apomorphine by about 63%. A similar study with sublingual apomorphine has not been conducted.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>